Hostmaster, querido amigo, he encontrado otro análisis en AVForums donde le dan un 8 a la calidad de imagen. En general les ha gustado pero en determinadas escenas han encontrado aliasing y moiré, aunque los analistas piensan que está motivado por la conversión que han tenido que realizar de 3D a 2D, ya que esta película ha sido rodada íntegramente en 3D.

...Digitally there are no compression problems, no banding or posterization, but, and here is where things go a little awry, there are a fair few instances of aliasing and moiré, which should never been seen on a CG animated film – the former is most apparent on buildings which occasionally shimmer as the edges waver (look at city hall during Megamind’s first entrance), while the latter can be seen in brickwork and clothing weaves (look at Roxanne’s shoulder when Hall is asking her to his place). Now, this is quite easily seen if you are looking for it, as I was, but those that aren’t looking with a critical eye (and with a properly calibrated setup) may never notice it. So, why is it there? Personally I think it’s an artefact left over from the 3D to 2D conversion...
Saludos, El Nota.