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One of Sheckley's early works, the 1953 Galaxy short story "Seventh Victim", was the basis for the film The 10th Victim, also known by the original Italian title La decima vittima. The film starred Marcello Mastroianni and Ursula Andress. A novelization of the film, also written by Sheckley, was published in 1966. The story may also have been the inspiration for the role-playing game Assassin.
The 1958 short story "The Prize of Peril" was adapted in 1970 as the German TV movie Das Millionenspiel, and again in 1983 as the French movie Le Prix du Danger. Written about a man who goes on a TV show in which he must evade people out to kill him for a week in order to win a large cash prize, it is perhaps the first-ever published work predicting the advent of reality television. There are many similarities between Sheckley's story and Stephen King's novel, "The Running Man", published in 1982, of which a film adaptation was later made.